2021.09.03 07:30
https://www.medpagetoday.com/infectiousdisease/covid19vaccine/94344
Fauci: 'Dramatic Data' From Israel Support COVID-19 Boosters | MedPage Today
2021.09.03 07:39
2021.09.03 08:20
Thanks for the assurance, doc.
I am gonna have it today as WM suggested.
BB
2021.09.03 09:39
I just went out to nearby pharmacy and got the booster shot, finally!!!
Thanks for all these supports!
BB
P.S. Now how long this booster effect would last?
2021.09.03 12:49
Only time will tell. This is the first Covid pandemic for all of us.
We might end up taking the Covid shot once every year.
I will be more than glad to get it annually.
2021.09.03 16:35
My wife and I got Pfizer 3rd shot today. I did exactly what WM
suggested. But Dr. Faucci said that COVID19 vaccination would be
completed by the 3rd shot. Sooner or later 3rd shot will be required.
2021.09.03 18:34
Good for you, Dr. Ohn! Then, what was the interval from the second shot? 6 months?
BB Lee
2021.09.03 17:11
https://apple.news/AClVzW1ZNQPyaD1bqQXaK
The daily count of new infections is rising in almost every part of the country, according to data tracked by The Washington Post. But only some places — mostly Southern states with lower vaccination rates — are seeing a parallel surge in deaths. The seven-day average of daily deaths is about a third of what it was in January, the pandemic’s most deadly month, but it is forecast to continue rising as high numbers of patients are hospitalized.
While most regions with increasing deaths have lower vaccination rates, that isn’t the case for all of them.
2021.09.03 17:22
CNN)The Pfizer/BioNTech Covid-19 vaccine booster plan remains on track for the week of September 20, according to a source familiar with the discussion, but it may take a few weeks longer to move forward with boosters of Moderna's vaccine.
There have been internal conversations within the Biden administration about scaling back the ambitious booster plan laid out by top federal health officials last month as the calendar nears September 20, when officials initially said boosters could be available for people who had either mRNA Covid-19 vaccine. A person familiar with the matter told CNN there was a meeting between top federal health officials and White House staff on Thursday in which officials warned that more time may be needed before enough data is in to recommend boosters for all adults, the person said.
Federal health officials relayed that Moderna's submission was "found inadequate and needs strengthened data" from the company, a source said. The company announced on Twitter Friday that it has completed the submission of its data on booster doses to the FDA. The agency is already evaluating data submitted by Pfizer/BioNTech for approval of a booster dose.
The Pfizer process remains on track, with the FDA's Vaccine and Related Biological Products Advisory Committee meeting set for September 17, the source said.
Moderna announced Wednesday it began submitting booster data to the FDA.
"These things happen and are part of the process," the source said. "We have and will continue to follow the science."
The New York Times was first to report on the discussion about scaling back the booster shot plan.
FDA officials previously tried to get the White House to not put a specific date on when people should expect Covid-19 booster shots, but they did anyway. White House coronavirus response coordinator Jeff Zients and federal health officials have repeatedly said the September 20 booster rollout was pending signoff from the FDA and US Centers for Disease Control and Prevention. White House spokesman Chris Meagher echoed those thoughts Friday.
"We always said we would follow the science and this is all part of a process that is now underway. We are awaiting a full review and approval by the FDA and a recommendation by the (Advisory Committee on Immunization Practices). When that approval and recommendation are made, we will be ready to implement the plan our nation's top doctors developed so that we are staying ahead of this virus," Meagher said in a statement.
The FDA still doesn't have enough data on Covid-19 booster shots yet, FDA Acting Commissioner Dr. Janet Woodcock said Thursday, despite the White House's September 20 planned start date.
"Why would you announce this? Well, we need to have a plan and the plan would involve the vaccination of very large numbers of people in the United States with a booster dose," Woodcock told Dr. John Whyte of WebMD during a virtual interview published online Thursday.
"We have to make a plan somewhat before we have all the data and I think that John is what's confusing people," Woodcock said.
Woodcock added that even though the FDA doesn't have all the data it needs yet on booster doses, the studies are coming soon.
"It is true that we don't have all the data," Woodcock said. "We don't have all the data on the boost, all the safety data, and so forth. Those studies have been completed and should be available to the FDA soon."
It's likely that three doses of Moderna or Pfizer coronavirus vaccine will end up being the recommended full regimen for protecting people from Covid-19 infection, Dr. Anthony Fauci said Thursday, noting that it's up to the FDA to make the final decision.
Fauci pointed to two Israel-based studies that showed a decrease in infections among people who got the third shot.
"But I must say from my own experience as an immunologist, I would not at all be surprised that the adequate full regimen for vaccination will likely be three doses," Fauci, who is director of the National Institute of Allergy and Infectious Diseases, said at the White House Covid-19 response team's briefing.
Waiting a few months in between doses allows the immune system to develop a full and mature response, which is then helped by a boost, he said.
"It is entirely understandable why the results that I just reported from the Israeli boost is so dramatic," Fauci said. "And we all hope and I believe we have good reason to believe that that only will not be a strong response, but that it will actually be durable, and if it is durable, then you're going to have very likely a three-dose regimen being the routine regimen."
Much relies on data that Moderna and Pfizer present to support their FDA applications, he said.
If FDA and the CDC's Advisory Committee on Immunization Practices endorse a booster dose, the federal government will promote it, Zients said.
"Once the FDA and ACIP make their recommendations on boosters, that same intensity of operations and coordination and partnership will be applied to the booster campaign," Zients said.
Johnson & Johnson is also studying the possibility of adding a second dose as a booster to its one-shot vaccine.
This story has been updated with additional details on Friday.
2021.09.03 18:34
If let the people wait to get 3rd shot for 8 months particularly with Pfizer,
there could be the widow of opportunity for delta varient to surge.
It may start on Sept. 20, but I think waiting 8 month after 2nd is too long.
I got my 2nd shot in March 22 and 3rd shot today.
2021.09.03 18:40
So, you think there wouldn't be no benefit to wait for 8 months for Moderna as well?
My wife got Moderna last March like many other peoplesso that she did not reach quite 8 months yet!
Opinion?
BB
2021.09.03 19:57
I think Moderna can wait a little longer than Pfizer, but Dr. Faucci
basically defines the vaccination as the completion of the 3 shots.
Why wait?
2021.09.03 20:26
It might make the difference between the first and second shot, either 2 weeks or 4-5 weeks.
My speculation is that it won't make much difference between waiting 6 months or 8 months.
Antibody maturity may matter in the first 2-4 weeks (between the 1st and 2nd shot).
But, after a few months later, it won't make much difference (?).
Remember, there's the one-year interval between the first and second (final) shot for Shingles.
But, in Covid, the breakthrough can happen much earlier (before 12 months).
But I am talking "out of my own head" without any scientific evidence.
As they say, the third shot makes a big difference in antibody formation.
If that's the case, why wait 8 months instead of 6 months?
Anyway, none of us know for sure yet. This is our first Covid experience!
2021.09.04 08:27
Thaaaaanks for all these additional opinions/recommendations! It gives a great helps to understand better on this antibody production business!
So, for Moderna vaccine, the 6-month interval for the booster shot should be OK!?
Will plan to let my wife get her booster shot of Moderna vaccine this month rather than waiting for another month.
Thanks, guys.
BB Lee
2021.09.04 08:28
It certainly makes more sense!
Thanks, doc.
BB Lee
Our WM's advice in regard to Pfizer booster shot is in the right tract
according to this latest data.
I recently had my healthy 85 year old accountant go for Pfizer booster
6 months after the second dose overruling his family doctor's advice
telling him to wait 8 months.