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Brain Initiative Unveiled

Report by Lauren Wolf & Susan Morrissey
"Chemical & Engineering News," April 8, 2013



    The White House announced last week  a new initiative
    to help understand the workings of the human brain.
    With a proposed initial federal investment of $100 million,
    President Obama called the effort to map the dynamics
    of human nerve cells the "next great American Project." "As humans, we can identify galaxies light years away;
    we can study particles smaller than an atom,"
    Obama said, "But we still haven't unlocked the mystery
    of the three pound of matter that sits between our ears."

    The Brain Initiative aims to follow in the footsteps of
    the Human Genome Project. ... The federal investment
    for the first year of funding for the genome project, 1988,
    was only $28 million.

    As proposed, three agencies will participate in the initiative.
    They are the Defense Advanced Research Project Agency,
    the NIH, and the National Science Foundation.
    The initiative will have support from private partners,
    including the Allen Institute for Brain Science, the Howard
    Hughes Medical Institute, the Kavli Foundation, and
    the Salk Institute for Biological Studies.

    A group of neuroscientists has been charged with coming
    up with a plan, specific goals, and an estimated milestone
    time frame for the project.

    The initiative will build on recent studies in neuroscience
    research. For instance, researchers can now record the
    firing of a few thousand neurons in animals.
    And they can get a coarse-grained look at how regions
    of the human brain are connected by using techniques
    such as functional MRI.

    But the human brains  contains 85 billion neurons, and
    those cells connect through an estimated 100 trillion
    junctions or synapses.

    This initiative, called BRAIN(Brain Research through
    Advancing Innovative Neurotechnologies), will help
    understand the dynamic connectivity of nerve cells,
    which could help treat conditions such as autism and
    schizophrenia, in which faulty neuronal circuitry has
    been implicted.

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