2020.04.27 02:47
Early Heparin therapy improves hypoxia in COVID-19 patients
https://www.news-medical.net/news/20200426/Early-Heparin-therapy-improves-hypoxia-in-COVID-19-patients.aspx
2020.04.27 03:00
2020.04.27 07:04
I think the terminal event of Coronavirus pneumonia may be the systemic disseminated intravascular coagulation
with sudden multi-organ failures (liver and kidney) that are so overwhelming that nothing can be done by doctors
except just helplessly watching the patient die. This is just like in the case of fulminating sepsis.
In this regard, the viral sepsis seems to have the same effect as the usual bacterial sepsis.
I would agree that Intravenous Heparin drip may be an excellent idea.
Just my speculation... I have no clinical experiences of DIC in viral sepsis.
In the latest article, there was one very important finding in the care of COVID-19 cases.
Application of respirator: When respirator was applied under sedation, there was about 50% mortality,
meaning only a half survives to get weaned from the respirator.
But in the case of no-respirator application, there were many more percentage of survivors.
In this case, the patient just resisted his agony of severe breathing difficulties with the help of physicians.
Their conclusion was that respirator actually damaged the lung. It shouldn't be applied until the very last desperation.
For us, this does not mean anything since we won't be in the position of treating COVID-19.
The important point is that when "I" get caught the COVID-19 and fall into the respiratory difficulty,
I should fight "not to get the respirator" to the very last conscious breath.
Try to avoid the respirator by all means. I would personally refuse respirator until I completely pass out.
Only then, doctors can intubate my throat according to the pre-written consent of mine.
I don't know how many of you agree with me. But that's what I would do if I get COVID-19.
This doesn't apply to other kinds of respiratory failures.
In other cases, I would apply respirator much earlier before it gets too late.
As an only thoracic surgeon in my county, these respirator businesses had been my main practice.
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This retrospective study seems to make pathophysiological sense
to explain the clinical improvements they observed in patients presenting
with hypoxia to their ICU.
Doctors in ICU need all the help and new ideas they can find, and
this idea may be one of those we can implement right away with a minimal risk.
Internists and cardiologists of my generation lived with heparin in our daily practices
so that it is something any doctor can initiate easily, I believe.