2018.07.02 00:54
2018.07.02 01:00
2018.07.02 08:04
2018.07.02 10:47
1. 홍삼 정도 가끔 먹고, 인삼차 도 가끔 마시고 예날에 산삼 도 한 쪼가리 얻어 먹었는 데, 기억력은 점점 떠러지니 ㅡㅡㅡ이 논문의 senior 저자인 분당 병원 정신과 교수 에게 따져?? 보겠읍니다. ㅎ. ㅎ
2. Ginseng, garlic, ginko, 먹는 한국인들이 심장수술후 피가 많이 나는것은 제 경험상 틀림 없읍니다...
어쩌면 intervention 후 하는 dual antiplatelet theraphy guide line 등도 제대로 하려면 , 한국인들 따로 study 해서 American Cardiology
guideline 과 다르게 써야 될런지도 모르지요.
2018.07.02 14:53
Thank you, Dr. Choh, for the comment.
One of our alumni who does cosmetic surgery
always makes sure to stop Ginseng weeks before surgery.
Theoretically Ginseng can rarely cause cerebral hemorrhage
just as the aspirin is known to do although I don't believe
it has ever been reported.
2018.07.03 04:40
Do you know “Arizona Green Tea with Ginseng and Honey?
It is a good size soft drink. It is a bit bigger than regular cola can.
‘Enjoy America’s best selling ready-to-drink green tea! Arizona Green Tea....
Where great taste and goodness naturally come together.
Green tea for its health benefits. Ginseng for energy and nature’s natural
sweenter, honey”
-from the can
Believe it or not;
If you drink it in the golf course, you can drive the ball 5 yard longer and you will not
miss any 5 foot put because ginseng will bring you more energy and improve your cognitive function.
2018.07.03 05:05
Thank you for sharing the top secret, Dr. Ohn.
My golf game is so bad I'm ready to try anything.
2018.07.04 02:54
"Theoretically Ginseng can rarely cause cerebral hemorrhage "
Hemorrhagic CVA continues to be major cause of death in Korea, especially females.
You may recall , when we were medical sstudents or interns in Korea during 60's and 70's, more than 50%
of CVA were hemorrhagic CVA. If you'd do spinal tap in ER for CVA pts those days, blood came out freqquently.
It decreased down to 20-25 % of CVA( 75 to 80 % being ischemic CVA) these days, it is still substantially higher than US population(10-15% being hemorrhgic of all CVA vs ischemic).
I don't know how much due to poorly controlled hypertension, salty food, or garlic/ginseng/ginko, frequent food supplements, or all of above. However , we see there is fairly rapid trend of decreasing hemorrhagic CVA(i.e. westernization of CVA patterns) in Korea every few years.
2018.07.04 03:16
I've been aware of the higher incidence of the hemorrhagic stroke in Korea than in the USA.
Since you brought the subject up, perhaps you might consider encouraging your younger colleagues there
to further investigate the possible contributing causes as a research subject.
Certainly the high incidence of hypertension related to the high salt intake
in combination with chronic lifetime intake of Ginseng may well be one of the nice recipes for
the hemorrhagic stroke.
I do not believe there has been a good research for the mechanism in regard to how Ginseng increases
the bleeding diathesis. suspect Ginseng may be affecting the platelet function. I may check out further
whether or not if there were any hematologic studies done in this regard.
2018.07.04 09:24
Research paper
Effect of non-saponin fraction from Panax ginseng on cGMP and thromboxane A2 in human platelet aggregation
Author links open overlay panelHwa-JinParkMan-HeeRheeKyeong-MeeParkKi-YeulNamKi-HyunPark
Show more
https://doi.org/10.1016/0378-8741(95)01317-2Get rights and content
The non-saponin fraction (NSF; lipophilic fraction) from the roots of Panax ginseng inhibited the aggregation of human platelets induced by thrombin (0.1 units/ml) in a dose-dependent manner. NSF induced the elevation of cGMP concentration in human platelets in a similar manner to molsidomine, a known vasodilator. NSF also inhibited Ca2+-influx into platelets. While verapamil, a Ca2+-antagonist, increased the cAMP level in platelets stimulated by thrombin, NSF had little effect on cAMP formation. Instead, NSF potently inhibited the thromboxane A2 (TXA2) production. The results suggest that NSF may regulate the levels of cGMP and TXA2to inhibit platelet aggregation induced by thrombin.
2018.07.04 10:30
The herbal medicines listed here all seem to have anticoagulant side effects so that it appears they all could
contribute to the high incidence of cerebral hemorrhage among Koreans.
2018.07.04 14:41
I did mention to cardiologists and surgeons about the need for such research in the past but clinicians
not much interested in platelet function analysis-etc type of research,
which may require sophisticated lab-works, I will mention some young hematologists and cardiologists again.
Anesthesia paper is very interesting in that they recommend to DC Garlic, 7 days before surgery, which might be an impossible task for Koreans,
There are so many TV programs promoting Herbal medicine like vegetables or Herbal food product.
It is disgusting. My brother-in-law used to take 9-10 roasted garlic every day for many years after such TV program.
At least Ginseng doesn't seem to do any harm.
It improves cognitive function but doesn't prevent cognitive disorder such as dementia.
However, excessive use of it is known to cause some significant side effects.
Trouble sleeping is the most common side effect. Less common effects include headache, agitation, upset stomach, menstrual problems (e.g., unusual vaginal bleeding), breast pain, and dizziness. An increase or decrease in blood pressure may also occur. Siberian ginseng may also cause drowsiness, nervousness, or mood changes.(from Internet)
Cardiologists are aware excessive intake of Ginseng can induce tachyarrhythmia, and Ginseng increases bleeding tendency.
Ginseng should be stopped before any surgery to minimize postoperative bleeding.