2021.02.21 08:06
2021.02.21 08:09
2021.02.21 08:56
It seems very logical and natural to reach a conclusion that people who had COVID already
would need only one more vaccination because the first infection is equivalent to the first vaccination. No big deal. Just common sense.
From this phrase in the above article,
"In that study, most people had been infected with the coronavirus eight or nine months earlier,
but saw their antibodies increase by a hundredfold to a thousandfold when given the first dose
of a vaccine. After the second dose, however, the antibody levels did not increase any further."
I can guess that the third vaccination will not make much difference in persons
who was not infected by COVID.
This seems to resolve my riddle of "What if I get the third vaccination?"
See, where I live (in Colorado), I have a unique situation where I can get Covid vaccination
in two different counties, meaning the third or/and the fourth shot is easily available to me.
Because one county does not know if I had two vaccinations already in the other county.
The question of "the third shot" came to my mind when my second vaccination did not give me
significant side reactions at all, meaning that my body did not get upset on the second stimulation.
Thus, I thought the second shot didn't do much for my antibody formation.
According to this study, the third shot may not do much good for me.
2021.02.22 09:48
We might need the third or one more booster shot to keep the immune system remain alert down the road though we really don't know aging-dependent ability or capacity rather retain the memory to produce proper antibodies when the time comes to encounter after all. Indeed as an old-timer transplant surgeon with a fixed(?) concept on the immune system, I still feel uneasy about this newly developed concept based on the messenger RNA to organize the vaccine rather than alive, though attenuated, or at least dead viruses with skepticism. Indeed, the immune system I learned through the experiment on the development of 'antilymphocytic serum', I spent so much time in my active days of transplant immunology, is an 'alive' system, not a 'static' system, with a tremendous variability! So I can't help but remain uneasy with such a new vista of immune reaction to a small piece of chemical/mRNA they rely on to generate enough memories/stimulations not only to the T-cell but also B-cell system linked with humoral antibody as well.
BB Lee
P.S. Though I am helplessly born as a pessimistic person, my personal guess(?) on the durability of the vaccine we took, based on my humble experiences on the transplant immunology, is perhaps 6 months or 1 year to keep sufficient(?) titers and regretfully we might have to go all over again like a shingle vaccine, who knows, a year or later!
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This is a very useful information for those who
had COVID19. It appears they just need one vaccination shot.