2020.05.16 01:19
2020.05.16 01:33
2020.05.16 01:43
DNA sequencing is the process of determining the nucleic acid sequence – the order of nucleotides in DNA. It includes any method or technology that is used to determine the order of the four bases: adenine, guanine, cytosine, and thymine. The advent of rapid DNA sequencing methods has greatly accelerated biological and medical research and discovery.[1][2]
Knowledge of DNA sequences has become indispensable for basic biological research, and in numerous applied fields such as medical diagnosis, biotechnology, forensic biology, virology, and biological systematics. Comparing healthy and mutated DNA sequences can diagnose different diseases including various cancers,[3] characterize antibody repertoire,[4] and can be used to guide patient treatment.[5] Having a quick way to sequence DNA allows for faster and more individualized medical care to be administered, and for more organisms to be identified and cataloged.[4]
The rapid speed of sequencing attained with modern DNA sequencing technology has been instrumental in the sequencing of complete DNA sequences, or genomes, of numerous types and species of life, including the human genome and other complete DNA sequences of many animal, plant, and microbial species.(from Internet)
RNA-Seq (named as an abbreviation of "RNA sequencing") is a particular technology-based sequencing technique which uses next-generation sequencing (NGS) to reveal the presence and quantity of RNA in a biological sample at a given moment, analyzing the continuously changing cellular transcriptome.[2][3]
Specifically, RNA-Seq facilitates the ability to look at alternative gene spliced transcripts, post-transcriptional modifications, gene fusion, mutations/SNPs and changes in gene expression over time, or differences in gene expression in different groups or treatments.[4] In addition to mRNA transcripts, RNA-Seq can look at different populations of RNA to include total RNA, small RNA, such as miRNA, tRNA, and ribosomal profiling.[5] RNA-Seq can also be used to determine exon/intron boundaries and verify or amend previously annotated 5' and 3' gene boundaries. Recent advances in RNA-Seq include single cell sequencing and in situ sequencing of fixed tissue.[6](from Internet)
2020.05.16 04:07
https://news.joins.com/article/23778390?cloc=joongang-home-toptype1basic
봉지에 갇힌 천산갑…중국서 야생동물 밀매가 사라지지 않는 이유
[출처: 중앙일보] 봉지에 갇힌 천산갑…중국서 야생동물 밀매가 사라지지 않는 이유
Scientists theorized by doing genetic sequencing study that
the coronavirus started from the bat, then went to pangolin, then to humans.
This headline news strongly supports these scientists' conclusions.
The article says Vietnam alone since 2000 was supplying one million of pangolin
to the Chinese black market by smuggling.
It seems this is the end of the story as far as the origin and the pathway of the virus
to humans are concerned.